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ELUCIDATING MECHANISMS THAT LEAD TO PERSISTENT ANXIETY-LIKE BEHAVIOR IN RATS FOLLOWING REPEATED ACTIVATION OF CORTICOTROPIN-RELEASING FACTOR RECEPTORS IN THE BASOLATERAL AMYGDALA
anxiety corticotropin-releasing factor somatostatin amygdala basolateral amygdala
2015/5/21
Anxiety disorders are estimated to impact 1 in 4 individuals within their lifetime. For some individuals, repeated episodes of the stress response leads to pathological anxiety and depression. The str...
Medial Expression of TNF-α and TNF Receptors Precedes the Development of Atherosclerotic Lesions in Apolipoprotein E/LDL Receptor Double Knockout Mice
atherosclerosis lipoproteins TNF-α TNF receptors
2009/4/20
TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, stimulates the release of proinflammatory cytokines and matrix metalloproteinases and promotes smooth ...
Muscarinic and 5-HT4 receptors participate in the regulation of the frequency of spontaneous contractions of the longitudinal muscle in rat distal colon
Muscarinic 5-HT4 receptors participate spontaneous contractions longitudinal muscle
2009/3/3
Spontaneous contractions of the intestine are thought to play an important role in the gastrointestinal motility, including peristalsis. In the present study, we investigated mechanisms for regulati...
Prostaglandin facilitates afferent nerve activity via EP1 receptors during urinary bladder inflammation in rats
Prostaglandin facilitates EP1 receptors urinary bladder inflammation rats
2009/3/2
We examined the effects of loxoprofen, a cyclooxygenase inhibitor, and ONO-8711, an EP1-receptor antagonist, on afferent nerve activity during acetic acid (AA, 0.1% v/v)-induced inflammation of the ...
Effect of a neuraminidase inhibitor（oseltamivir）on mouse jump-down behavior via stimulation of dopamine receptors
neuraminidase inhibitor mouse jump-down behavior stimulation of dopamine receptors
2009/3/2
Oseltamivir (Tamiflu®, Roche Laboratories, Inc.) is a neuraminidase inhibitor that can cause jumpdown behaviors in children. There is a mouse slip-down model, in which the dopamine D2 receptor a...