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Defining the Role of Matrix Compliance and Proteolysis in Three-Dimensional Cell Spreading and Remodeling
extracellular matrix Proteolysis
2010/1/7
Recent studies have identified extracellular matrix (ECM) compliance as an influential factor in determining the
fate of anchorage-dependent cells. We explore a method of examining the influence of E...
Dose-Dependent Cell Growth in Response to Concentration Modulated Patterns of FGF-2 Printed on Fibrin
Tissue engineering Inkjet technology Solid freeform fabrication Growth factor Printing technology Biological patterning
2009/12/22
Immobilized patterns of unmodified fibroblast growth factor-2 (FGF-2), with varying surface concentrations, were inkjet printed onto
physiologically relevant fibrin substrates. Printed patterns were ...
Relationship between NK Cell Activation and Clinical Response in Rheumatoid Arthritis Treated with Rituximab
Rheumatoid arthritis Rituximab NK cells variation
2009/10/30
Introduction: We investigated the relationship between the anti CD20 therapy and the NK cell phenotype in patients with Rheumatoid Arthritis (RA).
Methods: patients with seropositive RA according ...
Effects of Cyclic Strain and Growth Factors on Vascular Smooth Muscle Cell Responses
Cyclic Strain Growth Factors Proliferation Gene Regulation Vascular Smooth Muscle Cells
2010/1/22
Under physiological and pathological conditions, vascular smooth muscle cells (SMC) are exposed to different biochemical factors and biomechanical forces. Previous studies pertaining to SMC responses ...
In vivo chemotherapeutic profile of human gallbladder small cell carcinoma
human gallbladder small cell carcinoma
2009/3/2
Small cell carcinoma of the gallbladder is very rare, but shows high malignant potential with frequent metastasis. Chemotherapeutic regimens for the treatment of gallbladder small cell carcinoma hav...
Decreased expression of claudin-1 is correlated with recurrence status in esophageal squamous cell carcinoma
Decreased expression claudin-1 recurrence status esophageal squamous cell carcinoma
2009/3/2
Claudins are transmembrane proteins and major constitutes of tight junctions, and participate in the paracellular barrior and cellular connecting functions. They have been shown to be differentially...
The Role of Matrix Metalloproteinase-2 in the Remodeling of Cell-Seeded Vascular Constructs Subjected to Cyclic Strain
Tissue engineering Matrix metalloproteinases Mechanical properties Cyclic strain Vascular remodeling
2010/1/7
Tissue engineering offers the opportunity to develop
vascular substitutes that mimic the responsive nature of native
arteries. A good blood vessel substitute should be able to remodel
its matrix in...