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Mann-Whitney Test with Adjustments to Pre-treatment Variables for Missing Values and Observational Study
Dimension reduction Kernel smoothing Mann-Whitney statistic
2016/1/20
The conventional Wilcoxon/Mann-Whitney test can be invalid for comparing treatment effects in the presence of missing values or in observational studies. This is because the missingness of the outcome...
Qualitative implication and equivalence relations between treatment effects on surrogates and endpoints
Causal effect Prentice’s criterion Surrogate endpoint
2016/1/19
By the criterion for surrogates proposed by Prentice (1989), a null treatment effect on a surrogate implies a null treatment effect on a true endpoint.In this paper, we show that there may exist simul...
Adjusting for Treatment Effects in Studies of Quantitative Traits
Quantitative traits Imputation QTL mapping Single-marker analysis Mixed models Kruskal-Wallis test
2013/6/14
A population-based study of a quantitative trait, e.g. Blood Pressure(BP) may be seriously compromised when the trait is subject to the effects of a treatment. Without appropriate corrections this can...
Supplementary Appendix for "Inference on Treatment Effects After Selection Amongst High-Dimensional Controls"
Supplementary Appendix "Inference on Treatment Effects After Selection Amongst High-Dimensional Controls"
2013/6/14
In this supplementary appendix we provide additional results, omitted proofs and extensive simulations that complement the analysis of the main text
Estimating treatment effect heterogeneity in randomized program evaluation
Causal inference individualized treatment rules LASSO moderation variable selection
2013/6/14
When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers mus...
Performance guarantees for individualized treatment rules
Decision making l1-penalized least squares value
2011/6/17
Because many illnesses show heterogeneous response to treatment,
there is increasing interest in individualizing treatment to patients
[Arch. Gen. Psychiatry 66 (2009) 128–133]. An individualized
t...