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Advances in our understanding and management of sarcomas–rare bone and soft tissue cancers
sarcomas rare bone and soft tissue cancers
2015/4/21
Bone and soft tissue sarcomas are rare, accounting for approximately 1% of all adult solid malignant tumors. Although these cancers are categorised under the same banner of ‘sarcoma’, they in fact rep...
Adipose Tissue Insulin Action and IL-6 Signaling after Exercise in Obese Mice
INFLAMMATION MACROPHAGE ACUTE EXERCISE ADIPOSE TISSUE
2017/4/20
Introduction: Adipose tissue insulin action is impaired in obesity and is associated with inflammation, macrophage infiltration, and polarization toward a proinflammatory phenotype. Acute exercise can...
Tissue banking and its role in clinical and biological advances in oncology
oncology biological advances
2015/4/8
Basic scientific and clinical translational progress in oncology has progressed at an exponential rate over the last 40
years. Much of this progress was germinated in the laboratory, where rigorous ...
The biopsy of bone and soft tissue sarcoma is an integral part in the management of patients with these disorders and inadequate, inappropriate or inaccurate non-representative biopsies do lead to poo...
Role of pulmonary metastasectomy in osteosarcoma and soft tissue sarcoma
pulmonary metastasectomy osteosarcoma and soft tissue sarcoma
2015/4/1
There are no randomised control trials to guide the management of patients with potentially resectable lung metastases from osteosarcoma and soft tissue sarcoma, however evidence from retrospective co...
Principles of limb sparing surgery in bone and soft tissue sarcoma
limb sparing surgery in bone soft tissue sarcoma
2015/4/1
The standard for local control of malignant bone and soft tissue tumours has been amputation. Advances in multimodality treatment have seen a shift towards preservation of the limb. Sophisticated tech...
Role of radiation therapy in the management of soft tissue sarcoma
radiation therapy soft tissue sarcoma
2015/4/1
External beam radiation therapy (pre-operative or post-operative) is an essential part of limb conservation in the management of soft tissue sarcoma of the extremity. The addition of radiation therapy...
The role of radiology in assessing bone and soft tissue sarcomas encompasses the initial detection and diagnosis of the lesion, staging the lesion both locally and systemically, guiding biopsy of the ...
Cancer clinical trials are research studies that test whether new or modified approaches to
the prevention, diagnosis or treatment of cancer are safe and effective. Some trials may also
explore as...
Tunable hydrogels for pancreatic tissue engineering
Tunable hydrogels pancreatic tissue engineering
2015/1/12
Type I diabetes is an autoimmune disorder characterized by the loss of insulin producing islet cell mass. While daily insulin injection provides an easy means of glycemic control, it does not prevent ...
Analysis of the Bioelectric Impedance of the Tissue-Electrode Interface Using a Novel Full-Spectrum Approach
electrode impedance
2015/1/12
Non-invasive surface recording of bioelectric potentials continues to be an essential tool in a variety of research and medical diagnostic procedures. However, the integrity of these recordings, and h...
The 37th International Sun Valley Workshop on Skeletal Tissue Biology: Foreword
The 37th International Sun Valley Workshop Skeletal Tissue Biology
2014/12/4
The W.S.S. Jee Remodeling in Bone (RIB) Award was given to Dr. David Baylink, who spoke about "The IGF System in the Rise and Fall in Bone Density with Age". This presentation generated lively discuss...
Characteristics and Outcomes of Patients with Vasoplegic Versus Tissue Dysoxic Septic Shock
sepsis septic shock hyperlactatemia lactate mortality
2014/11/28
Background: The current consensus definition of septic shock requires hypotension after adequate fluid challenge or vasopressor requirement. Some patients with septic shock present with hypotension an...
Fatty acid composition of adipose tissue and colorectal cancer: a case-control study
biomarkers colorectal cancer desaturase elongase fatty acids
2018/12/20
Background: Unlike experimental results, epidemiologic studies that used dietary questionnaires were not convincing as regards the relations between dietary fatty acids (FAs) and risk of colorectal ca...
Ultrastructural elastic deformation of cortical bone tissue probed by NIR Raman spectroscopy
Raman bone biomechanics
2014/11/6
Raman spectroscopy is used as a probe of ultrastructural (molecular) changes in both the mineral and matrix (protein and glycoprotein, predominantly type I collagen) components of murine cortical bone...