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THERAPEUTIC IMPLICATIONS OF COMPUTER MODELS OF BRAIN ACTIVITY FOR ALZHEIMER DISEASE
COMPUTER MODELS
2015/7/31
Neural models of large-scale brain processes help to explain many features of neuropsychological syndromes and psychiatric disease. Two associative memory models useful to understand some aspects of c...
Novel regulation of neuronal genes implicated in Alzheimer disease by microRNA
Alzheimer APP BACE1 microRNA post-transcriptional gene regulation amyloid fetal neurons
2015/5/21
Alzheimer disease (AD) results, in part, from the excess accumulation of the amyloid-β peptide (Aβ) as neuritic plaques in the brain. The short Aβ peptide is derived from a large transmembrane precurs...
EVALUATION OF GENE REGULATION AND THERAPEUTIC DRUGS RELATED TO ALZHEIMER’S DISEASE IN DEGENERATING PRIMARY CEREBROCORTICAL CULTURES
Alzheimer synapse neurodegeneration primary culture memantine
2015/5/21
Alzheimer’s disease (AD) is a neurological disorder defined by the presence of plaques comprised mostly of amyloid-β (Aβ), and neurofibrillary tangles consisting of hyperphosphorylated microtubule ass...
MRI Measures of Neurodegeneration as Biomarkers of Alzheimer's Disease
magnetic resonance imaging (MRI) Alzheimer's disease (AD) mild cognitive impairment (MCI) biomarkers cognitive complaints Alzheimer's Disease Neuroimaging Initiative (ADNI) visual contrast sensitivity
2015/5/21
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease. Many researchers believe that an effective AD treatment will prevent the development of disease rather than treat the...
Automatic Detection of Associatons Among Terms Related to Alzheimer's Disease from Medline Abstracts
Alzheimer disease
2015/1/9
Automatic Detection of Associatons Among Terms Related to Alzheimer's Disease from Medline Abstracts.
Increasing Self-care Ativities for Caregivers of Persons with Alzheimer’s Disease and Other Dementias to Reduce Burden and Depression
caregiver self-care burden, depression
2014/10/22
Caregivers in the United States are a rapidly growing segment of the system of care for those with Alzheimer’s disease and other dementias. Lack of training and support puts them at risk of depression...
Treatment of Alzheimer’s Disease in Iranian Traditional Medicine
Alzheimer’s Disease Traditional Medicine Diet Lifestyle
2015/10/16
Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disease with a high prevalence in recent years. Dramatic growth in AD prevalence has increased the importance of more researches...
Understanding the individual with Alzheimer’s disease: Can socioemotional selectivity theory guide us?
Alzheimer’s Disease Socioemotional Selectivity Theory Individual Differences Awareness Positivity Bias Socialization
2013/1/28
Individuals often get lost behind the diagnosis of Alzheimer’s disease (AD) while widespread differences between these patients are more common than similarities. Socioemotional Selectivity Theory (SS...
Certain new aspects of etiology and pathogenesis of Alzheimer’s disease
Alzheimer's Disease CDR TDR Dementia Vascular Factors in Alzheimer’s Disease
2013/1/28
The research focuses on the possibility of early detection of AD-specific vascular and atrophic brain changes in families which have a tendency to inherit the disease. The research included three fami...
Comparison of protein concentrations in serum versus plasma from Alzheimer’s patients
Alzheimer’s Disease Serum Proteins Plasma Proteins
2013/1/28
Background: There is great interest in developing blood-based biomarkers for Alzheimer’s disease (AD); however, there is no consensus as to what blood fraction is most appropriate for analyzing partic...
Prevalence of cerebrospinal fluid Alzheimer disease-like pattern in atypical dementias
CSF Alzheimer Disease Atypical Dementias Frontotemporal Dementia Corticobasal Syndrome Progressive Supranuclear Palsy
2013/1/28
BACKGROUND: Differential diagnosis between Frontotemporal Dementia (FTD), Corticobasal Syndrome (CBS), Progressive Supranuclear Palsy Syndrome (PSP), FTD with motor neuron disease (FTD-MND) is often c...
CSF tau and amyloid β42 levels in Alzheimer’s disease—A meta-analysis
Alzheimer’s Disease Dementia CSF Amyloid β42 CSF Tau Meta-Analysis
2013/1/28
Alzheimer’s disease International (ADI) estimates that there are currently 30 million people with dementia in the world. The main objective was to perform meta-analysis of studies of CSF tau and Amylo...
Neural correlates of focused attention in patients with mild Alzheimer’s disease
fMRI Focused Attention Stroop Alzheimer’s Disease
2013/2/20
Alzheimer’s Disease (AD) is characterized by an early and significant memory impairment, and progresses to affect other cognitive domains. Impairments in Focused Attention (FA) have been observed in p...
Depressive Symptom Endorsement among Alzheimer’s Disease, Vascular Dementia and Mild Cognitive Impairment
Depression Cognitive Impairment Alzheimer’s Vascular Dementia Mild Cognitive Impairment
2013/8/30
Background: The Geriatric Depression Scale (GDS) is widely used to assess depressive symptoms in clinical and research settings. This study utilized a 4 factor solution for the 30-item GDS to explore ...
Depressive Symptom Endorsement among Alzheimer’s Disease, Vascular Dementia and Mild Cognitive Impairment
Depression Cognitive Impairment Alzheimer’s Vascular Dementia Mild Cognitive Impairment
2013/1/31
Background: The Geriatric Depression Scale (GDS) is widely used to assess depressive symptoms in clinical and research settings. This study utilized a 4 factor solution for the 30-item GDS to explore ...