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SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells
SARS-CoV-2-encoded nucleocapsid protein acts viral suppressor of RNA interference cells
2020/6/12
We thank Prof. Peng Zhou (Wuhan, China) for kindly providing materials and thank Yan Wu and Weijuan Shang for experimental assistance. This work was supported by the Strategic Priority Research Progra...
Microbial modulation of innate defense: goblet cells and the intestinal mucus layer
goblet cells mucins mucus
2016/6/14
The gastrointestinal epithelium is covered by a
protective mucus gel composed predominantly of mucin glycoproteins
that are synthesized and secreted by goblet cells.
Changes in goblet cell function...
Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells
endothelial cell reactive oxygen species rats
2016/6/13
Flavonoids may exert their health benefit in cardiovascular
disease by modulating monocyte adhesion in the
inflammatory process of atherosclerosis. Most in vitro studies
used forms of flavonoids pr...
Chocolate procyanidins decrease the leukotriene-prostacyclin ratio in humans and human aortic endothelial cells
Chocolate eicosanoids flavonoids
2016/6/12
Polyphenolic phytochemicals inhibit vascular and
inflammatory processes that contribute to disease. These effects
are hypothesized to result from polyphenol-mediated alterations
in cellular eicosan...
Effect of trans fatty acids on calcium influx into human arterial endothelial cells
atherosclerosis umbilical cord magnesium
2016/6/1
A recent task force of The American Society for
Clinical Nutrition and American Society for Nutritional Sciences
recommended in a position paper on trans fatty acids that
models be developed to ass...
Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements
Lycopene phytofluene carotenoids
2016/6/1
Lycopene has been identified as a phytochemical
with potentially protective health benefits.
Effects of high compared with low calcium intake on calcium absorption and incorporation of iron by red blood cells in small children
Calcium absorption iron absorption preschool children
2016/5/31
The potential benefits of increasing calcium
intake in small children must be balanced with the potential risk
to iron utilization from high calcium intakes.
Exercise on Progenitor Cells in Healthy Subjects and Patients with Type 1 Diabetes
DIABETES BLOOD CIRCULATION ENDOTHELIUM
2017/4/13
Purpose: To evaluate the acute effect of aerobic exercise (AE) and resistance exercise (RE) on the release of endothelial progenitor cell (EPCs, CD34+/KDR+/CD45dim) and vascular function in type 1 dia...
Prenatal Maternal Physical Activity and Stem Cells in Umbilical Cord Blood
REAST STEM CELLS CARDIOVASCULAR FITNESS EARLY LIFE DETERMINANTS
2017/4/13
Purpose: Early life processes, through influence on fetal stem cells, affect postnatal and adult health outcomes. This study examines the effects of physical activity before and during pregnancy on st...
Down regulation of miR-203 in radiation- induced thymic lymphoma promoted cells proliferation and inhibited apoptosis
TANK-binding kinase 1 (TBK1) SLUG (SNAI2) Cyclin D1 (CCND1)
2015/11/24
To investigate the role of miR-203 in radiation-induced thymic lymphoma (RITL).Methods A 60Co irradiator was used for total-body irradiation. MicroRNAs(miRNAs) level was assayed by qRT-PCR. Cell proli...
Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
RNA Synthesis in the Tracheal Epithelial Cells of Aging Mice as Revealed by Electron Microscopic Radioautography
RNA synthesis Macromolecular Microscopic radioautography 3H-uridine
2015/7/21
For the purpose of studying the aging changes of macromolecular synthesis in the tracheal epithelial cells of experimental animals, we studied 10 groups of aging mice during development and aging from...
FUNCTIONAL GENOMICS STUDY TO UNDERSTAND THE ROLE OF SEROTONIN IN MOUSE EMBRYONIC STEM CELLS
Serotonin mouse embryonic stem cells
2015/5/26
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that is synthesized from the amino acid L-tryptophan and is reported to localize in mitochondria of embryonic stem cells. Even bef...
ROLE OF OVARIAN CANCER-INITIATING CELLS IN HIGH-GRADE SEROUS OVARIAN CARCINOGENESIS
Epigenetics DNA Methylation Carcinogenesis
2015/5/26
A subpopulation of tumor cells known as ovarian cancer initiating cells (OCICs) have been shown to be the cells that propagate the tumor phenotype in ovarian cancer. Studies have showed that a very sm...
Endothelial Colony Forming Cells (ECFCs): Identification, Specification and Modulation in Cardiovascular Diseases
Corneal endothelium Endothelial progenitor cells Arterial endothelial cell differentiation
2015/5/25
A hierarchy of endothelial colony forming cells (ECFCs) with different levels of proliferative potential has been identified in human circulating blood and blood vessels. High proliferative potential ...