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肿瘤微环境(tumor microenvironment,TME)在肿瘤恶性和治疗抵抗中发挥着重要作用。近年来,根据TME特点挖掘潜在靶点并开发安全有效的免疫疗法逐渐成为乳腺癌治疗的研究热点。2018年7月27日,复旦大学生物医学研究院/附属肿瘤医院柳素玲团队在PLOS Biology杂志在线发表了题为CCL20 triggered by chemotherapy hinders the ther...
2021年11月,山西医科大学公共卫生学院劳动卫生学教研室牛侨教授团队在《Molecular Therapy-Nucleic Acid》(JCR1区、中科院2区,影响因子8.886)在线发表题为“Whole-transcriptome analysis of aluminum-exposed rat hippocampus and identifification of ceRNA network...
Currently, there are no approved specific antiviral agents for novel coronavirus disease 2019 (COVID-19). In this study, 10 severe patients confirmed by real-time viral RNA test were enrolled prospect...
Background: Overfeeding can lead to multiple metabolic and clinical complications and has been associated with increased mortality in the critically ill. Continuous venovenous hemofiltration (CVVH) re...
Background: Approximately 50% of newly diagnosed cancer patients start taking dietary supplements. Men’s health supplements (MHSs), which we define as supplements that are specifically marketed with t...
Background: Parenteral fish-oil (FO) therapy is a safe and effective treatment for intestinal failure–associated liver disease (IFALD). Patients whose cholestasis does not resolve with FO may progress...
Alterations in body composition have been reported in HIV-positive adults receiving highly active antiretroviral therapy (HAART), but the magnitude and potential determinants of these changes are u...
Pancreatic enzyme replacement therapy frequently fails to correct intestinal fat malabsorption completely in cystic fibrosis (CF) patients. The reason for this failure is unknown.
Pancreatic cancer is a highly lethal disease due to its late presentation and its innate resistance to treatment. Although much research has been conducted in order to discover and develop new therape...
Background: Ectopic pregnancy (EP) is one of the most dangerous complications of pregnancy and without prompt diagnosis and treatment, it could become a major cause of maternal morbidity and mortality...
The androgen signalling axis is critical for the development and progression of prostate cancer. Therefore, the mainstay treatments for metastatic disease are hormonal manipulations aimed at reducing ...
Background: Multiple sclerosis (MS) is a central nervous system disorder with periods of recurrence and recovery. Mitoxantrone has been approved for secondary progressive MS (SPMS) treatment but data ...
Background: Despite the insufficient evidence, due to potential contribution to the improvement, platelet-rich plasma (PRP) is emerging as a promising method.
Background: Patient satisfaction is the most important criterion in evaluating the quality of care. Besides, its assessment in patients with severe mental disorder treated by electroconvulsive therapy...

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