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Depletion of Thymus-Derived CD4+CD25+ T Cells Abrogates the Suppressive Effects of α-galactosylceramide Treatment on Experimental Allergic Conjunctivitis
allergic conjunctivitis eosinophils regulatory T cells thymus α-galactosylceramide
2010/11/17
α-GalCer treatment significantly suppressed EC in the thymus-intact mice that had not been treated with anti-CD25 Ab. In contrast, α-GalCer treatment of thymectomized and anti-CD25 Ab-treated mice did...
Possibility of non-steroidal treatment in allergic conjunctival diseases
allergic conjunctival disease corticosteroid immunosuppressive agent non-steroidal anti-inflammatory drug vernal keratoconjunctivitis
2010/11/22
In a recent epidemiological study, 15-20% of the population in Japan was estimated to have allergic conjunctivitis. Allergic conjunctival diseases (ACD) have a wide spectrum of clinical severity and t...