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Gene Expression Profiles of BAD and Bcl-xL in the CA1 Region of the Hippocampus Following Global Ischemic/Reperfusion and FK-506 Administration
Ischemic/Reperfusion Real-Time RT-PCR Hippocampus Tacrolimus Bcl-xL Gene BAD
2015/12/29
Background: The hippocampus is a tiny nub in the mammalian brain that is involved in forming, organizing, and storing memories. Global cerebral ischemia (GCI) and reperfusion induced apoptosis lead to...
Investigating Antithyroid Effects of Propylthiouracil on the Ischemia and Reperfusion Injury in Rat’ Kidney and Determining the Role of Nitric Oxide in Mediating this Effect
Ischemia Reperfusion Rat,Renal Transplantation
2015/10/15
Background: Renal ischemia/reperfusion injury (IRI) is a major problem in renal transplantation, which occurs during the process of organ retrieval and storage, and is closely associated with acute re...
Effects of Losartan and Vanillic Acid Co-Administration on Ischemia-Reperfusion-Induced Oxidative Stress in Isolated Rat Heart
Oxidative Stress Injury Vanillic Acid Losartan
2015/10/13
Background: Experimental studies have demonstrated that angiotensin II (ANG-II)-induced oxidative stress contributes to the pathogenesis of I/R injury.
Effects of Gallic Acid and Cyclosporine A on Antioxidant Capacity and Cardiac Markers of Rat Isolated Heart After Ischemia/Reperfusion
Antioxidant Capacity Cyclosporine A Ischemia Reperfusion Gallic Acid Myocardial Infarction
2015/10/13
Background: Myocardial infarction is one of the important causes of death during old ages. Gallic acid as an antioxidant or cyclosporine A (CsA) as inhibitor of mitochondrial permeability transition p...
The effect of Nitroprusside on the renal ischaemia-reperfusion injury
Nitroprusside Ischaemia-reperfusion
2009/12/24
Nitric oxide (NO) is implicated as an important mediator of, or intermediary in, inflammation, immunity and neurotransmission. In the kidney, No is involved in haemodynamic regulation, control of vasc...
Could Mean Platelet Volume Predicts Impaired Reperfusion and In-Hospital Major Adverse Cardiovascular Event in Patients with Primary Percutaneous Coronary Intervention after ST-Elevation Myocardial Infarction?
Myocardial infarction Heart Catheterization Reperfusion
2009/12/18
Background: Due to the positive relation between platelet size and platelet reactivity, a high value of the mean platelet volume (MPV) is an independent risk factor to predict acute myocardial infarct...
Effects of hydroalcoholic extract of Cynodon dactylon (L.) pers.on ischemia/reperfusion-induced arrhythmias
Cynodon dactylon (L.) pers. ischemia/reperfusion arrhythmias isolated heart rat
2009/12/17
Background and purpose of the study: Probable antiarrhythmic effects of Cynodon dactylon (L.) pers. (family Poaceae) against ischemia/reperfusion (I/R)-induced arrhythmias were investigated in isolate...
Ischemia-Reperfusion Injury,Reactive Oxygen Metabolites,and the Surgeon
Ischemia-Reperfusion Injury Reactive Oxygen Metabolites
2009/7/3
Surgeons are confronted with ischemia-reperfusion (IR) injury more often than they anticipate. Hypoperfusion associated with hypotension and hypovolemia is probably the most common cause of non-occlus...
New Frontiers in The Reperfusion of Myocardial Infarction
Myocardial infarction reperfusion thrombolysis
2009/6/30
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality (1). It is estimated that around 30% of patients die within the first hour of the onset of symptoms (2). In-hospital mort...
The Effects of Allopurinol on Stomach Mucosal Barrier of Rats Subjected to Ischemia-Reperfusion
Ischemia and reperfusion stomach mucosal barrier allopurinol
2009/6/30
The present experimental study was carried out on rats subjected to ischemia and reperfusion. The effects of allopurinol on mucus, an important component of the stomach mucosal barrier, were investiga...
Bacterial Translocation after Partial Hepatic Resection under Ischemia and Reperfusion in Rats:Incidence and Time Course
liver ischemia major hepatectomy bacterial translocation endotoxin TNF-a
2009/6/24
Infectious complications are major causes of morbidity and mortality following major hepatic resection. We investigated in rats the incidence and time course of bacterial translocation after partial h...
Effects of ACE Inhibition and AT1 Receptor Blockade on Cardiac Ischaemia-Reperfusion Induced Mortality and Cardiac Markers in Rats
Myocardial Ischemia-Reperfusion Arrhythima Cardiac Marker Troponin Captopril Losartan
2009/6/22
Many studies have established the therapeutic benefits of angiotensin-converting enzyme (ACE) inhibitors such as reducing reperfusion arrhythmias, and angiotensin II type 1 (AT1) blocker may have simi...
Activation of the Nuclear Factor Kappa B Pathway Following Ischemia-Reperfusion of the Murine Testis
Testicular oxidative stress apoptosis NF-B activation
2008/12/23
Ischemia-reperfusion (IR) of the testis results in testicular oxidative stress and germ cell-specific apoptosis. Nuclear factor kappa B (NF-B) is a nuclear transcription factor involved in the control...
Ischemia reperfusion dysfunction changes model-estimated kinetics of myofilament interaction due to inotropic drugs in isolated hearts
Ischemia reperfusion dysfunction model-estimated kinetics myofilament interaction inotropic drugs
2010/2/26
We found that IR injury resulted in reduced myofilament Ca2+ sensitivity, and decreased cross-bridge association and dissociation rates. Dopamine (8 μM) reduced myofilament Ca2+ sensitivity before, bu...
Postconditioning:A new link in nature’s armor against myocardial ischemia/reperfusion injury
link myocardial ischemia/reperfusion injury
2014/3/31
Area at risk myocardium after reperfusion harvested and stained with Dihydroethidium fluorescence (DHE) to visually assess generation of superoxide anions. A: IR group; B and C: area at risk myocardiu...