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Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes.
Exogenous delivery chaperonin fragment ApiCCT modulates mutant Huntingtin cellular phenotypes
2015/12/11
Aggregation of misfolded proteins is characteristic of a number of neurodegenerative diseases, including Huntington disease (HD). The CCT/TRiC (chaperonin containing TCP-1/TCP-1 ring) chaperonin compl...
Mutations of TYR and MITF Genes are Associated with Plumage Colour Phenotypes in Geese
Goose TYR and MITF Gene SNP Plumage Colour
2016/5/16
The polymorphism of microphthalmia-associated transcription factor (MITF) and tyrosinase (TYR) genes have been proposed to play a vital role in coat colour genesis in mammals, but their role remains a...
Molecular and Cellular Mechanisms Leading to Similar Phenotypes in Down and Fetal Alcohol Syndromes
Down Syndrome Fetal Alcohol Syndrome Caspase 3 Dyrk1a Rcan1 Akt
2015/5/22
Down syndrome (DS) and Fetal Alcohol Syndrome (FAS) are two leading causes of birth defects with phenotypes ranging from cognitive impairment to craniofacial abnormalities. While DS originates from th...
Dynamic phenotypes as criteria for model discrimination: fold-change detection in R. sphaeroides
Dynamic phenotypes criteria model discrimination fold-change detection R. sphaeroides Molecular Networks
2012/4/28
The chemotaxis pathway of the bacterium Rhodobacter sphaeroides has many similarities to the well-studied pathway in Escherichia coli. It exhibits robust adaptation and has several homologues of the l...
Plastic phenotypes of antennule shape in Bosmina longirostris controlled by physical stimuli from predators
antennule shape Bosmina longirostris controlled
2014/4/22
Three antennule morphotypes in the small cladoceran Bosmina longirostris have been considered to be
hereditarily rigid phenotypes. However, we found that monoclonal populations of Bosmina collected f...
Newly discovered reproductive phenotypes of a marine copepod reveal the costs and advantages of resistance to a toxic dinoflagellate
Newly discovered reproductive phenotypes the costs and advantages of resistance
2014/4/22
We document for the first time toxin-resistant reproductive phenotypes of copepods and we describe a novel
procedure to identify these phenotypes. Individual copepods of the species Acartia hudsonica...