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Down regulation of miR-203 in radiation- induced thymic lymphoma promoted cells proliferation and inhibited apoptosis
TANK-binding kinase 1 (TBK1) SLUG (SNAI2) Cyclin D1 (CCND1)
2015/11/24
To investigate the role of miR-203 in radiation-induced thymic lymphoma (RITL).Methods A 60Co irradiator was used for total-body irradiation. MicroRNAs(miRNAs) level was assayed by qRT-PCR. Cell proli...
Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
RNA Synthesis in the Tracheal Epithelial Cells of Aging Mice as Revealed by Electron Microscopic Radioautography
RNA synthesis Macromolecular Microscopic radioautography 3H-uridine
2015/7/21
For the purpose of studying the aging changes of macromolecular synthesis in the tracheal epithelial cells of experimental animals, we studied 10 groups of aging mice during development and aging from...
FUNCTIONAL GENOMICS STUDY TO UNDERSTAND THE ROLE OF SEROTONIN IN MOUSE EMBRYONIC STEM CELLS
Serotonin mouse embryonic stem cells
2015/5/26
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that is synthesized from the amino acid L-tryptophan and is reported to localize in mitochondria of embryonic stem cells. Even bef...
ROLE OF OVARIAN CANCER-INITIATING CELLS IN HIGH-GRADE SEROUS OVARIAN CARCINOGENESIS
Epigenetics DNA Methylation Carcinogenesis
2015/5/26
A subpopulation of tumor cells known as ovarian cancer initiating cells (OCICs) have been shown to be the cells that propagate the tumor phenotype in ovarian cancer. Studies have showed that a very sm...
Endothelial Colony Forming Cells (ECFCs): Identification, Specification and Modulation in Cardiovascular Diseases
Corneal endothelium Endothelial progenitor cells Arterial endothelial cell differentiation
2015/5/25
A hierarchy of endothelial colony forming cells (ECFCs) with different levels of proliferative potential has been identified in human circulating blood and blood vessels. High proliferative potential ...
IMPACT OF ALCAM (CD166) ON HOMING OF HEMATOPOIETIC STEM AND PROGENITOR CELLS
endosteal bone marrow vascular bone marrow flow cytometry
2015/5/25
The potential of hematopoietic stem cells (HSC) to home and to anchor within the bone marrow (BM) microenvironment controls the ability of transplanted HSCs to establish normal hematopoiesis. Activate...
Shp2 deletion in post-migratory neural crest cells results in impaired cardiac sympathetic innervation
Shp2 pERK Bradycardia
2015/5/25
Autonomic innervation of the heart begins in utero and continues during the neonatal phase of life. A balance between the sympathetic and parasympathetic arms of the autonomic nervous system is requir...
Tsg-6 : an inducible mediator of paracrine anti-inflammatory and myeloprotective effects of adipose stem cells
Adipose stem cell inflammation TSG-6 hematopoiesis smoking
2015/5/22
Tumor necrosis factor-induced protein 6 (TSG-6) has been shown to mitigate inflammation. Its presence in the secretome of adipose stem / stromal cells (ASC) and its role in activities of ASC have been...
Reconstitution of mouse inner ear sensory development from pluripotent stem cells
Inner ear Pluripotent stem cells Hair cells
2015/5/21
The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound. Hearing loss and imbalance are primarily caused by degeneration of the mechanosensitive hair cells i...
Engraftment of bone marrow-derived cells after nonlethal radiation in syngeneic C57BL/6 mice
Chimerism Bone marrow-derived cells Nonlethal radiation
2015/11/24
To study the characteristics of cell engraftment in mice at a lower dose under nonlethal radiated condition.Methods A syngeneic C57BL/6 mouse model, transplanted with 1×107 bone marrow cells and expos...
Expression of Glucose Transporter 4 (GLUT4) is Increased by Cinnamaldehyde in C2C12 Mouse Muscle Cells
Glucose Transporter type 4 Cinnamaldehyde Real-Time Polymerase Chain Reaction Diabetes Mellitus Insulin
2015/10/10
Background:: In diabetes mellitus because of the absence or insufficient sensitivity to insulin, glucose transporter protein in cell membrane, glucose transporter 4, is decreased. GLUT4 is the major g...
A variety of cell types are important components of the immune system. They constitute some of the body’s main defences against infection.
Resistance Exercise Increases Endothelial Progenitor Cells and Angiogenic Factors
Vascularendothelialgrowthfactor matrixmetalloproteinases muscleendurance muscleischemia
2017/5/17
Introduction: Bone marrow-derived endothelial progenitor cells (EPC) are involved in vascular growth and repair. They increase in the circulation after a single bout of aerobic exercise, potentially r...
Adipose Tissue Derived Multipotent Mesenchymal Stromal Cells Can Be Isolated Using Serum-free Media
Mesenchymal Stem Cells Cariel Culture Medium Cell Therapy
2015/9/30
Background: Mesenchymal stromal cells (MSCs) as multipotent cells with the capacity to be differentiated into several cell lineages are promising sources for cell therapy and tissue engineering nowada...