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Renal cell carcinoma is the most common neoplasm of the kidney comprised of different histological variants. Chromophobe renal cell carcinoma (ChRCC) is a rare subtype of renal cell carcinoma (RCC) ma...
Cytomorphological Diagnosis of Giant Cell Tumour of Distal End Radius in Elderly Patient
Benign bone tumour Cytology Giant cell tumour
2015/7/10
Giant cell tumours (GCTs) of bone have been described as the most challenging benign bone tumors. It is very unusual for GCT to occur in patients younger than 20 yrs or older than 55 years. GCT is see...
Metastatic Renal Cell Carcinoma in the Sinonasal Region
Sinonasal region Metastatic renal cell carcinoma Diagnosis
2015/7/10
Sinonasal region is an exceptional site for metastatic tumors. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. Clear cell carcinoma is i...
CHEMOTHERAPY AND BIOLOGICAL AGENTS IN THE CLINICAL MANAGEMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA
CHEMOTHERAPY BIOLOGICAL AGENTS
2015/3/20
Historically surgery and subsequently radiotherapy became established as the primary treatments for head and neck
squamous cell carcinoma. The significant incidence of recurrence and metastasis in pa...
FDG PET: Revolution or evolution in the management of non-small cell lung cancer?
Revolution evolution management of non-small cell lung cancer
2015/3/11
Lung cancer is currently the leading cause of cancer-related death in both men and women in most Western countries. In Australia there is a falling incidence in males that is not matched in females, t...
Contemporary management of non-small cell lung cancer in Australia
Contemporary management non-small cell lung cancer Australia
2015/3/11
In 1955, Bromley and Szur reported on 66 patients with a pathologic diagnosis of lung cancer who had been treated with high dose radiotherapy and who had then proceeded to surgery1. In 24 (46.7%) no t...
Cytotoxic effects of caffeic acid phenethyl ester (CAPE) on the human multiple myeloma cell line
Caffeic acid phenethyl ester (CAPE) multiple myeloma cytotoxicity IL-6
2010/1/11
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the i...
Investigation of p53 codon72 polymorphism in oral squamous cell carcinoma (SCC) specimens and normal population by PCR
Squamous cell carcinoma Mouth neoplasm Codon Genotype Exon Polymorphism p53 Polymerase chain reaction
2009/12/7
Background and Aim: A single nucleotide polymorphism at codon 72 of the p53 gene alters the p53 protein structure and affects its activity. This polymorphism depends on geographic regions and race. Al...
G2 checkpoint abrogation as a cancer specific,cell cycle disruption
Cell Cycle G2 checkpoint DNA damage Chemo-sensitization Oncogenesis
2009/7/15
The majority of cancer cells are thought to have accumulated the necessary mutations for oncogenesis as a result of disrupting the cell cycle G1 checkpoint, leading to the replication of damaged DNA. ...
The death receptor TRAIL in cancer cell apoptosis
Death receptor Fas TNF-α TRAIL cancer apoptosis
2009/7/15
Apoptosis is a key regulator or tissue homeostasis. Death ligands and death receptors of the tumor necrosis factor (TNF) family play crucial roles in mediating apoptosis. TNF-related apoptosis-inducin...
An Epidemiologic study of Oral and Pharyngeal Nonsquamous Cell Malignant Tumors inKerman province,Iran
Epidemiology Pharyngeal cancer Oral malignant melano-ma Oral sarcoma Minor salivary gland tumor
2010/4/19
Objective: The aim of the present study was to estimate crude and age-standardized incidence rates for oral and pharyngeal nonsquamous cell malignant tumors in Kerman province over a period of 11 year...